Evaluation of lipid profile, malondialdehyde, hemoglobin and ferritin in Iraqi women with polycystic ovarian syndrome

Ashwaq A. Shenta
ID
Email src
Abbas D.M. Al-Maliki
ID
Mufid K. Abou-Turab
ID
Department of Chemistry, College of Education for Pure Sciences, University of Basrah, Basrah, Iraq
Department of Chemistry, College of Education for Pure Sciences, University of Basrah, Basrah, Iraq
Department of Biology, College of Education for Pure Sciences, University of Basrah, Basrah, Iraq
Received: 26 October 2024 / Revised: 11 January 2025 / Accepted: 13 January 2025 / Published: 30 June 2025

Abstract

Introduction and aim. The concept of polycystic ovarian syndrome (PCOS) is defined as a biochemical complex statement that affects many young and adult females (single and married). This case presents a variety of medical and biological concerns related to the reproductive system. The aim of the study was to investigate and estimate the levels of the lipid profile, malondialdehyde, hemoglobin and ferritin in women with PCOS.


Material and methods. Blood samples were collected from 180 women who were divided into 100 PCOS patients and 80 healthy women according to the variables of age and body mass index. Triglycerides (TG) levels were measured in blood sera by spectrophotometric method, total cholesterol (TC) levels were estimated using enzymatic methods and the high-density lipoprotein (HDL) was determined by the HDL-phosphotungstic acid precipitation method.


Results. Total cholesterol, triglyceride, low-density lipoproteins, and very low-density lipoproteins recorded a highly significant increase (p<0.001) whereas high-density lipoproteins decreased significantly (p<0.001) in women with PCOS women when compared to the control group depending on age and body mass index variables. The results showed that hemoglobin, ferritin and malondialdehyde levels increased significantly (p<0.001) in female PCOS compared to the healthy group according to age and body mass index variables.


Conclusion. The importance of thorough medical management of PCOS includes minimizing oxidative stress, metabolic function, and lipid profiles for avoidance of chronic health conditions.

 

Cite 

Shenta AA, Al-Maliki ADM, Abou-Turab MK. Evaluation of lipid profile, malondialdehyde, hemoglobin and ferritin in Iraqi women with polycystic ovarian syndrome. Eur J Clin Exp Med. 2025;23(2):378–385. doi: 10.15584/ejcem.2025.2.14.

 

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited