Therese David
Swetha Lakshmi Narla
Annapurneswari Subramanyan
Kathiresan N.
Secondary chondrosarcoma of the iliac bone in a young woman – a rare case report and review of the literature
Therese David
Swetha Lakshmi Narla
Annapurneswari Subramanyan
Kathiresan N.
Department of Histopathology, Apollo Hospitals, Chennai, India
Department of Histopathology, Apollo Hospitals, Chennai, India
Department of Histopathology, Apollo Hospitals, Chennai, India
Department of Surgical Oncology, Apollo Hospitals, Chennai, India
Received: 3 November 2024 / Revised: 10 February 2025 / Accepted: 23 February 2025 / Published: 30 June 2025
Abstract
Introduction and aim. Chondrosarcomas are malignant cartilage-forming tumors, with secondary cases rarely arising from osteochondromas. This report presents a case of secondary chondrosarcoma developing from an undiagnosed pelvic osteo chondroma in a young female, emphasizing the importance of early detection and timely intervention.
Description of the case. A 28-year-old woman with hip and back pain underwent magnetic resonance imaging, revealing a le sion in the left iliacus muscle with sacroiliac extension. Biopsy confirmed a chondroid neoplasm, and positron emission topog raphy-computed tomography showed minimal metabolic activity. Due to the extensive soft tissue component and recurrence risk, wide local excision was performed. Histology confirmed well-differentiated secondary chondrosarcoma, WHO grade 1 arising from an undiagnosed pre-existing osteochondroma.
Conclusion. The described case highlights the critical role of radiological and histopathological evaluation, timely surgical in tervention, and multidisciplinary management for optimal patient outcomes.
Cite
David T, Narla SL, Subramanyan A, Kathiresan N. Secondary chondrosarcoma of the iliac bone in a young woman – a rare case re port and review of the literature. Eur J Clin Exp Med. 2025;23(2):524–528. doi: 10.15584/ejcem.2025.2.25.
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